Реґіонарне застосування антибіотиків та препаратів йоду в комплексних схемах лікування корів за гнійного ендометриту

О. О. Боднар, С. П. Керничний, Т. В. Захарова, О. О. Боднар

Анотація


THE REGIONAL ADMINISTRATION OF ANTIBIOTICS AND IODINE PREPARATIONS IN COMPLEX TREATMENT REGIMENS COWS WITH PURULENT ENDOMETRITIS

 

О. О. Bodnar, S. P. Kernichniy, T. V. Zakharovа, О. О. Bodnar

 

Abstract.Theaimofresearchwas a scientificfoundationtodevelopandgiveclinicalevaluationofvariousregionalmodesofantibiotictherapyincombinationwithiodinecowswithpurulentendometritis. Torealizethisgoal, thestudyposedthefollowingproblem:

1. Tostudythespeciescompositionofmicroflorautero-vaginalsecretionsofsickcowsanddeterminethesensitivityofthesepathogenstoantimicrobialagents.

2. Tostudyincomparativeperspectivetherapeuticpossibilitiesofregionalmethodsofadministrationofiodine.

3. Optimizetreatmentforsuppurativeendometritiscowsbasedmethodsofrationaluseofdrugs, usingthesynergyoftheiraction.

Theresultsofclinicalandexperimentalstudiesoftheregionaluseofantibioticsandiodinepreparationsincomplextreatmentregimenscowswithpurulentendometritis. Thebasisofrationalcausalandsupportivetherapywasinitiated a regionaladministrationofdrugs: intheinternaliliacarteryfor IP Lipovtsevym, paravaginalnoandvaginally. WeredesignedandtestedcomplexsequentialcircuitstherapeutictreatmentofpatientsendometritiscowstestedgemotropnyeMethods (arteryandvein) administrationofdrugsindividually, andcombinationsthereof. Bacteriologicalstudieshaveidentifiedthebacterialflorawithpurulentexudate, isdefinedantibioticsensitivityabjection, whichwasconductedinaccordancewiththeselectionetiotropchnihdrugs. Clinicalstudieshaveestablishedthattheintramuscularinjectionofenrofloxacinandmetronidazolecombinedwithuterotonicdrugswaseffectivemethodoftreatmentofcowswithpurulentendometritis. Theregionaladministrationofthisdrugcombinationhasincreasedtheefficiencyoftreatmentandfertilizationofcowsandreducerelapse. Additionofthetherapeuticregimengemotropnimintroductionofanaqueousiodinesolutionmadeitanabsolutecurativeeffect, completelyeliminatedtherecurrenceandchronicityofinfectionintheuterus, contributedtotherestorationofreproductivefunctionofcowsrecover.

Intrasimultaneousapplication "broestrofana" and "dotsitola" duetosynergismoftheiractionsanddirectedadministrationacceleratedtheevacuationofpurulentexudatefromtheuterus, aswellasimprovedtreatmentoutcomesandindicatorsvosproizvodstvodstvarecoverfromcows.

Theproposedcombined a regionaluseofenrofloxacinandmetronidazolecombinedwithiodinetherapy, luteolyticanduterotrophicdrugscowswithpurulentendometritisprovedhighlyeffectivetherapy, reducedthecostoffundsformedicinesandgaveoptimalpharmacoeconomicindicatoroftreatmentthatcanbeattributedto a synergisticeffectofthiscombinationofantibioticssupplementedwithiodinetherapy, aswellastherationalmethodsoftheirapplication.


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Посилання


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