Інтенсивність пероксидного окиснення ліпідів уеритроцитах поросят за дії міцелярної формитокоферолу

О. В. ДАНЧУК, Р. В. ПОСТОЙ, В. В. Карповський, М. Р. КЛЮЦУК, В. М. Скрипкіна, В. І. Карповський, Т. Б. ЖЕЛТОНОЖСЬКА, Н. М. ПЕРМЯКОВА

Анотація


INTENSITY OF LIPID PEROXIDATION IN THE ERYTHROCYTES OF PIGS UNDER THE IMPACT OF TOCOPHEROL MICELLAR FORM

 

O. V. Danchuk, R. V. Postoy, V. V. Karpovskiy, M. R. Klyutsuk,

V. M. Skripkina, V. I. Karpovskiy, T. B. Zheltonozhskaya,
N. M. Permyakova

 

Abstract. The paper presents the results of studying the intensity of lipid peroxidation in erythrocytes of pigs under the impact of micellar form of tocopherol. Experiments were conducted on 20 pigs of large white breed 4 months of age who were fattening. Formed two groups of animals – control and experimental. Animals of experimental group were given nanodrug of vitamin E (micellar form of encapsulated α-tokopherol acetate) at a dose of 4.5 mg / kg for 10 days. Serum samples were tested for products of lipid peroxidation: diene conjugates, related trienes and Schiff bases.

Feeding piglets with micellar form of vitamin E for 10 days contributes to a significant decrease in the content of diene conjugates and Schiff bases in erythrocytes respectively 18.7 % and 30.0 % (p <0.05). Established probable strength impact of watering micellar form tocopherol on content of diene conjugates and Schiff bases in erythrocytes of pigs (η2x = 0.36–0.46; p <0.05).


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