Кістковий метаболізм у собак за ускладненого перебігу репаративного остеогенезу та заміщення кісткових дефектів остеотропними матеріалами

М. В. РУБЛЕНКО, В. М. ВЛАСЕНКО, С. А. СЕМЕНЯК

Анотація


BONE METABOLISM IN DOGS AT COMPLICATED REPARATIVE OSTEOGENESIS AND IN CASE OF BONE DEFECTS REPLACEMENT WITH OSTEOTOPIC MATERIALS

 

M. Rublenko, V. Vlasenko, S. Semenyak

Abstract.This article provides an assessment of reparative osteogenesis in dogs for specific bone biomarkers. In terms of today fractures of long bones in dogs of all surgical diseases account for 6-15 % and the fragmentation fracture can reach 60 %. However, complications of bone repair registered in 7-32 % of cases.

The aim of the study was to determine the status of bone metabolism complications reparative osteogenesis and its dynamics in cases of post-traumatic defects replacement femoral composite materials Biomin-GT and Collapan-liter.

The study was performed on dogs that came to the surgical clinic Bilotserkivskyi oskolchatymy NAU with diaphyseal femoral fractures and complicated course of reparative osteogenesis.

The results of the studies found that for comminuted fractures of the femur in dogs after osteosynthesis ekstrakortykalnoho developing intense and fleeting (by the 14th day) osteoblastychna reaction. Use osteotropic composites to replace bone defects and causes moderate long osteoblastychnu reaction that in the case of kolapanu somewhat hampered at the 7th and 30th day. However osteoclastic reaction for comminuted fractures of the femur has two peaks - the 7th and 60th day, and the use Collapan - the 7th, 14th and 60th. The use of Biomin accompanied by moderate osteoclastic reaction, starting with the seventh day after osteosynthesis.

Along with this, in the case of nonunion marked insufficient bone, and the development of suppurative osteomyelitis - a significant inhibition osteoblastychnoyi reaction against the backdrop of strengthening osteorezorbtsiyi.

In the future, further research by studying the bone metabolism consolidation of fractures with the use of other types osteoinduktyvnyh composites.


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Посилання


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