Розробка способу підвищення життєздатності новонароджених ягнят з використанням нанобіоматеріалів

П. М. СКЛЯРОВ, В. П. КОШЕВОЙ

Анотація


DEVELOPMENT method of INCREASING viability FOR NEWBORN lambs using nanobiomaterials

 

P. M. Sklyarov, V. P. Koshevoy

 

Abstract.The effective way to improve viability of newborn lambs using nanobiomaterials which was created based on a comprehensive drug «Caplaestrol + OV Zn», which provides normalization of homeostasis and improve the structure of placenta and fetus under development by streamlining the state of prooxidant-antioxidant and oxygen metabolism.

Specifically normal content in serum vitamin A, zinc and total protein; prooxidative-antioxidant system containing serum malondialdehyde, catalase, superoxide dismutase and erythrocyte malondialdehyde, catalase, reduced glutathione and oxidative-antioxidant value; system state oxygen metabolism – the number of erythrocytes and hemoglobin concentration of 2,3-bisphosphoglycerate.

Compared with the control group increased weight of newborn lambs to 374,5 g (11,7 %, P < 0,99), litter weight – 22,6 g (8,6 %, P < 0,999), the area of the placenta – 30,4 cm2 (8,7 %, P < 0,99) and the number cotyledons – 3,8 (4,6 %, P < 0,99).

In the long term expected testing other drugs that are based on nanobiomaterials, in order to reduce the cost and simplify the methods of their application.


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