Мікроскопічні зміни в печінці, нирках і підшлунковій залозі собак за експериментального ентерального саркоцистозу

Б. В. Борисевич, М. П. ПРУС, В. Є. Зворигіна

Анотація


MICROSCOPIC CHANGES IN THE LIVER, KIDNEYS AND PANCREAS OF DOGS IN CASE OF EXPERIMENTAL ENTERAL SARCOCYSTOSIS

 

B. V. Borisevich, M. P. Prus, V. E. Zvorygina

 

Abstract.ResearchsonthedistributionofsarcocystosisamongdogsinUkrainehavenotbeencarriedout. Inanaccessibleworldliteraturepostmortemchangesincaseofsarcocystosisofdogsaredescribedinsufficiently. Theaimofourstudywastoexaminemicroscopicchangesintheliver, kidneysandpancreasofdogsincaseofexperimentalenteralsarcocystosis. Theliver, kidneyandpancreasofthreepups, experimentallyinfectedwithSarcocystis, wereusedinourinvestigation. Forhistologicalstudies, selectedpiecesofthoseorganswerefixedin 10% neutralaqueoussolutionofformalinand, afterdehydrationinethanolsofincreasingconcentrationsandchloroform, wereembeddedinparaffin. Sliceswiththicknessof 7 - 10 micronswereobtainedbyusingsledgemicrotome. Todetectmicroscopicstructureoforganssectionswerestainedwithhematoxylinandeosin.

Intheliverofdogs, incaseofexperimentalenteralsarcocystosis, granulardystrophyanddestructionofthehepatocytesandinterlobularproliferationoffibrousconnectivetissuewererecorded. Inkidneysextracapillaryserousglomerulonephritisandgranulardystrophyofepitheliumofconvolutedandstraighttubulesweredetected. Inthepancreasmicroscopicallytheswelling, disruptionanddestructionofindividualacinusoftheglandwerefoundout. 


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