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Анотація


MICROSCOPIC CHANGES IN THE LIVER, KIDNEYS AND PANCREAS OF DOGS IN CASE OF EXPERIMENTAL ENTERAL SARCOCYSTOSIS

B. V. Borisevich, M. P. Prus, V. E. Zvorygina

Abstract.ResearchsonthedistributionofsarcocystosisamongdogsinUkrainehavenotbeencarriedout. Inanaccessibleworldliteraturepostmortemchangesincaseofsarcocystosisofdogsaredescribedinsufficiently. Theaimofourstudywastoexaminemicroscopicchangesintheliver, kidneysandpancreasofdogsincaseofexperimentalenteralsarcocystosis. Theliver, kidneyandpancreasofthreepups, experimentallyinfectedwithSarcocystis, wereusedinourinvestigation. Forhistologicalstudies, selectedpiecesofthoseorganswerefixedin 10% neutralaqueoussolutionofformalinand, afterdehydrationinethanolsofincreasingconcentrationsandchloroform, wereembeddedinparaffin. Sliceswiththicknessof 7 - 10 micronswereobtainedbyusingsledgemicrotome. Todetectmicroscopicstructureoforganssectionswerestainedwithhematoxylinandeosin.

Intheliverofdogs, incaseofexperimentalenteralsarcocystosis, granulardystrophyanddestructionofthehepatocytesandinterlobularproliferationoffibrousconnectivetissuewererecorded. Inkidneysextracapillaryserousglomerulonephritisandgranulardystrophyofepitheliumofconvolutedandstraighttubulesweredetected. Inthepancreasmicroscopicallytheswelling, disruptionanddestructionofindividualacinusoftheglandwerefoundout.


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