DETERMINATION OF INDICATORS CARBOHYDRATE METABOLISM IN THE ORGANISM OF ANIMALS UNDER THE ACTION OF THE MAGNETIC FIELD 50 HZ.
DOI:
https://doi.org/10.31548/dopovidi2017.02.003Keywords:
magnetic field of industrial frequency, glucose, glycogen, functional state, bioeffectAbstract
Topicality Last year the system of public health trends updated characterized by the formation of concepts and principles. Health of the nation is the source of success and prosperity of the state, the basis of life and prospects. According to WHO priority is preserving and improving human health. Continuously increasing attention to the health of the population from the effects of anthropogenic factors. One of these priorities is the development of environmental medicine safety criteria and methodologies improving hygiene research for health factors of different nature, including physical. However, intense economic and other human activities leading to environmental pollution, which along with chemical, electromagnetic radiation pollution in wide view.
Recent studies have confirmed the presence of quantitative relationships of environmental pollution and public health. This led to the justified concerns of scientists and people around the world (USA, Russia, Ukraine, Sweden, Japan and others). In this regard, WHO has included the problem of electromagnetic pollution in the list of priority problems of mankind. Analysis of published data on this issue has shown that the impact of this factor in urban areas each year becomes more and more noticeable to human health. The question of limiting the negative impact of environmental factors, determine safe levels of exposure to EMF health.
The aim of the study determining the content of glycogen and glucose in animals by the action of a magnetic field of 50 Hz.
Materials and methods Assessing the impact of magnetic field exposure is characterized by a reaction of the organism, ie biological response indicators for the functional state of the studied experimental conditions on animals. Studies conducted on white rats Wistar line in conditions of chronic experiment are exposed to a magnetic field of 50 Hz and the load level 10, 30 and 90 mkTl the daily eight-irradiation. The experimental animals were divided into groups of 10 animals each, according to the current level. Control group animals were kept in similar conditions but without exposure. The selection of biological material and registration rates in the period of the investigated factors held monthly, and 30 days after cessation of exposure. All results were processed using the statistical method of calculation criteria study t - Student. Blood glucose was determined using uniform methods of test set firm Sentinel (Italy). Quantitative glycogen content in tissue homogenates of liver and brain were determined by antronovym in Morris.
Results and discussion. The results showed that the effect of the magnetic body radiation test animals corresponds violation hydrocarbon processes in the blood and organs. The dynamics of chronic experiment revealed changes in blood glucose levels. So in groups of 10 and 30 mkTl glucose ranged in waves - it grew, it decreased relative to controls. In the group of 90 mkTl rate was reduced by 30, 60 and 90 days and increased by 120 per day and after a period of aftereffect. There have been no significant changes detected glucose liver homogenates, shown a decrease in its content relative control values in all experimental groups. Only groups of 10 and 30 mkTl 30 and 90 day rate increased relative to control values. Glucose concentration in homogenates of brain grew only in the group of 10 mkTl 30 and 90 days and a group of 90 to 30 days mkTl tended to decline relative to control values.
Number of glycogen in organs was assessed for its content in liver homogenates and brain. Index tended to decrease during the experiment in all groups experience. Only a group of 10 mkTl 60 and 90 day experiment of the increase, but did not go beyond the control values. Along with the glycogen content in the homogenates of brain ranges of control. A slight downward trend throughout the experiment noted in all groups load.
Increased blood glucose - hyperglycemia may be in hepatotoxicity. Hypoglycemia can be caused by disruption of glikogeneza and glycogenolysis, glucose increased cleavage tissues, enhanced glucose excretion through the kidneys. The processes of concentration and support the basic functions of biochemical substrates, their transformation reactions depend on the actions of various exogenous influences.
Conclusions and prospects. Studies have shown that glucose and glycogen in the blood and organs of animals change with the increase of time and action, that is the response of carbohydrate metabolism is dose-time dependence. Violation glycogenolysis and therefore decrease energy in the body that leads to stress adaptation mechanisms under the influence of a magnetic field. Features of metabolic disorders defined demonstrated implementation dependent adverse effects of magnetic fields on the body from the current level of MP and the factor of time. This dependence is an important argument in justifying safe levels MP 50 Hz for health.
References
Basic documents of the World Health Organization. (2009). Geneva, 261.
Serdiuk A. M., Dumanskiy Yu. D. (2004). Elektromahnitna bezpeka - suchasna hihiienichna problema, shliakhy yii vyrishennia. [Electromagnetic Safety - Modern Hygienic Problem, Ways to Solve it]. Proceedings of the XIV Congress of Hygienists Ukraine "Hygienic Practice and Science at the Turn of the Century" Dniprpetrovsk, 19-21 trav. 2004 r. - Dnipropetrovsk, 2004. Vol.1. 251-254 (in Ukrainian).
Dumanskiy V. Yu., Bitkin S. V., Dumanskiy Yu. D. et all (2014). Hihiienichna otsinka prostorovoho rozpodilu u navkolyshnomu seredovyshchi elektrychnoho ta mahnitnoho polia, shcho stvoriuietsia vitrovymy elektrostantsiiamy [Hygienic Assessment of the Spatial Distribution of Environmental Electric and Magnetic Fields Generated by Wind Power Plants] In : Hihiiena naselenykh mists [Hygiene of Settlements]. Kyiv. 64. 152-161 (in Ukrainian).
Hietanen M., Kovala T., Hamalainen A. M. (2000). Human brais activity during exposure to radiofrequency fields eminet by cellular phones. Scand. J. Work Environ Health, 26, 87-92.
https://doi.org/10.5271/sjweh.516
Owen R. D. (2000). Possible health risks of radiofrequency from mobile telephones. Epidemiology, Vol. 11, 2, 99-100.
https://doi.org/10.1097/00001648-200003000-00002
Grigoriev Yr. D. еd. (2002).Yelektromahnytnye polia y zdorove cheloveka [Electromagnetic Fields and Health Human]. Moscov: Mineral, 177. (in Russian).
Dumanskiy V. Yr., Bitkin S. V., Dumanskiy Yr. D. et all (2014). Hihiienichna otsinka priorytetnykh chynnykiv, shcho stvoriuiutsia vysokovoltnymy (110-330 kV) kabelnymy liniiamy elektroperedachi ta yikh obladnanniam [Hygienic Assessment of Priority Factors that Created High-Voltage (110-330 kV) Electricity Transmission Lines and their Equipment]. In : Hihiiena naselenykh mists [Hygiene of Settlements]. Kyiv, 63. 138-160. (in Ukrainian).
Sharapova A. M. (2012). Strukturni zminy v selezintsi shchuriv pislia oprominennia elektromahnitnym polem i nastupnomu vvedenni rozchynu ekhinatsei [Structural Changes in the Spleen of Rats After Exposure to Electromagnetic Field and the Next Administration Solution Echinacea]. Health Perspectives, Vol. XVII (4), 17-20 (in Ukrainian).
https://doi.org/10.24061/1727-0847.17.4.2018.3
Morgan R. W., Kelsh M. A., Zhao K. (2000). Radiofrequency exposure and mortality from cancer of the brain and Lymphatic/hematopoietic systems. Epidemiology, Vol.11 (2), 118-127.
https://doi.org/10.1097/00001648-200003000-00007
Temuryants H. A., Martynyuk V. S., Malyhyna V. N. (2007). Sostoianye sympatoadrealovoi systemy pry yzolyrovannom y kombynyrovannom s hipokynezyei deistvyem peremennoho mahnytnoho polia sverkhnyzkoi chastoty [Status Sympatoadrealovoy System With Insulated and Kombynyrovannom With Hypokinesia Action Peremennoho Frequency Magnetic Field Sverhnyzkoy]. Physics living, Vol 15 (2), 40-48 (in Russian).
Martynyuk V. S., Zeisler Y. V., Temurjants N. A. (2012). Ynterferentsyia mekhanyzmov vlyianyia slabykh yelektromahnytnykh polei kraine nyzkykh chastot na orhanyzm cheloveka y zhyvotnykh [Interference of the Mechanisms of the Influence of Weak Electromagnetic Fields of Extremely Low Frequencies on the Human and Animal Organism] Geophysical processes and the biosphere, V. 11 (1), 16-39 (in Russian).
Polka N. S., Dumanskiy V. Yr., Bitkin S. V. Dumanskiy Yr. D. et all (2015). Hihiienichna otsinka elektromahnitnoho vyprominiuvannia, shcho stvoriuietsia zasobamy WI-FI zasobamy, ta medyko-profilaktychni vymohy do yikh vykorystannia v navchalnomu protsesi zahalnoosvitnikh zakladiv [Hygienic Evaluation of Electromagnetic Radiation Generated by Means of WI-FI Facilities, and Medical and Preventive Requirements for Their Use in the Educational Process of Educational Institutions]. In : Hihiiena naselenykh mists [Hygiene of Settlements]. Kyiv, 66: 132-141 (in Ukrainian).
Kamyshnikov V. S. (2000). Spravochnyk po klynyko-byokhymycheskoi laboratornoi dyahnostyke [Handbook of Clinical and Biochemical Laboratory Diagnostics]. Minsk: Belarus, 495. (in Russian).
Belousova Z. P. (2004). Toksychnost khymycheskykh soedynenyi [Toxicity of Chemical Compounds]. PPPurigin .- Samara: Samara University Publishing House, 111. (in Russian).
Kamyshnikov K. N. ed. (2003). Klynyko-byokhymycheskaia laboratornaia dyahnostyka [Clinical and Biochemical Laboratory Diagnostics]. Moscov: Medicine, 652. (in Russian).
Tomashewska L. A. (2004). Rol biokhimichnykh doslidzhen v obgruntuvanni bezpeky elektromahnitnykh faktoriv dovkillia [The Role of Biochemical Studies to Substantiate the Safety of Electromagnetic Environmental Factors]. Proceedings of the XIV Congress of Hygienists Ukraine "Hygienic Practice and Science at the Turn of the Century" Dniprpetrovsk, 19-21 trav. 2004 r. - Dnipropetrovsk, 2004. Vol.1. 273-275. (in Ukrainian).
Dumanskiy Yu. D., Tomashevskaya L. A. (2006). Medyko-byolohycheskye aspekty vlyianyia mahnytnoho polia promyshlennoi chastoty [Medico-Fiological Aspects of the Influence of the Magnetic Field of the Industrial Frequency]. Results and perspectives of scientific research on the human ecology and environmental health, Human ecology, hygiene and medicine of the environment at the turn of the century: the state and development prospects, Moscov, 253-257. (in Russian).
Downloads
Published
Issue
Section
License
Relationship between right holders and users shall be governed by the terms of the license Creative Commons Attribution – non-commercial – Distribution On Same Conditions 4.0 international (CC BY-NC-SA 4.0):https://creativecommons.org/licenses/by-nc-sa/4.0/deed.uk
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
