INFLUENCE OF TRANSFER FACTOR ON LEUKOCYTES CONTENT AND LEUKOGRAM IN BLOOD OF CALVES

Authors

  • V. V. Postoy National University of Life and Environmental Sciences of Ukraine image/svg+xml
  • V. G. Skibitskiy National University of Life and Environmental Sciences of Ukraine image/svg+xml

DOI:

https://doi.org/10.31548/dopovidi2017.02.023

Keywords:

transfer factor, leukogram, leukocytes, leukocyte indices

Abstract

The article presents data on the impact of transfer factor obtained from bovine colostrum cells on leukocytes content and leukogram in blood of calves. Confirmed that during postnatal adaptation in calves naturally occurs leukopenia. Application of colostric transfer factor stimulates at this period increase of leukocytes content in blood of animals by 13-15 %, has effect on blood leukogram – increasing the proportion of lymphocytes, decreasing segmented neutrophils content, changing integral indicators – leukocyte and nuclear indices. 

References

Borvak, Y. Maier, V. (1990) Amynokyslotnyi analyz otdelnykh pykov hrubo y chastychno ochyshchennykh ultrafyltratov leikotsytov cheloveka, poluchennykh pry yspolzovanyy vysokoeffektyvnoi zhydkostnoi khromatohrafyy na obrashchennoi faze [The amino acid analysis of individual peaks of coarsely and partially purified human leukocyte ultrafiltrates obtained using high performance liquid chromatography on the reversed phase]. Acta Virol, 34, 1, 19-25.

Skybitskyi, V. H., Spivak, M. Ia., Stepaniuk, O. V., Pyshchyk, P. P., Karas, O. Ia., Kupchynskyi, H. V., Miskevych, S. V., Kozlovska, H. V. ,Taseu Solomon (2000) Metodychni rekomendatsii z otrymannia ta testuvannia faktora perenesennia aktyvnoho imunitetu proty patohennykh bakterii ta virusiv [Methodical recommendations obtaining and testing of transfer factor active immunity against pathogenic bacteria and viruses]. Kiev, 11. (in Ukraine)

Skybitskyi V. H. (2005) Metodolohichni aspekty imunolohii [Methodological aspects of immunology]. Naukovyi visnyk NAU, Vyp.89, 183-188. (in Ukraine)

Stepanyuk, O.V. (1999). Vlasty`vosti faktora perenesennya akty`vnogo imunitetu do zbudny`ka xvoroby` Auyeski [Properties of transfer factor of active immunity to the pathogen Aujeszky]. Kiev, Veterinary medicine of Ukraine, 9, 20-22.

Stolyuk, V. V., Sky`bicz`ky`j, V. G. (2003). Imunomodulyuyuchi vlasty`vosti transfer-faktora akty`vnogo imunitetu [Immunomodulatory properties of transfer factor active immunity]. Kiev, Journal of Agricultural Science,10, 32-34.

Stolyuk, V. V., Skybiczkyj, V. G. (2002). Vplyv antyrabichnogo transfer-faktoru na deyaki pokaznyky klitynnogo imunitetu morskych svynok [The influence of the antirabic transfer factor on some indices of cellular immunity of guinea pigs]. Kiev, Scientific Journal NAU, 50, 189–191.

Tashuta, O. S., Tashuta, S. G. (2008). Efektyvnist klinichnogo zastosuvannya eksperymentalnykh zrazkiv transfer-faktora dlya likuvannya hvorykh sobak [The effectiveness of clinical application of experimental models of transfer factor for treatment of dogs]. Kiev, NAU, 133-134.

Shreder, Y., Perepechkyna, N. P., Mats, A. N., Medunytsyn, N. V. (1979) Ad’yuvantnye svoystva preparatov transfer-faktora yz lymfotsytov myndalyn cheloveka [Adjuvant properties of transfer factor preparations from human tonsils lymphocytes] ZhMEY. 2, 103-108.

Bukowski, R. M., Deodhar, S., Hewlett, J. S., Greenstreet, R. (1983) Randomized controlled trial of transfer factor in stage (malignant melanoma ). Cancer, 51, 2, 269-272. https://doi.org/10.1002/1097-0142(19830115)51:2<269::AID-CNCR2820510217>3.0.CO;2-6

Burger D., Vanderbark A., Vetto R. (1983) Human Transfer Factor: specificity and structural models // Immunobiology of Transfer Factor / Eds. Kirkpatrik D., Burger H., Lowrence. New-York, 33-42. https://doi.org/10.1016/B978-0-12-409850-3.50009-7

Capman S. Kirkpatrik С. (1978) The two step leukocyte migration inhibition factor (LIF) .It is use in evaluation of cellular immune function In patients with Immunodeficiency diseases. Cell. lmmunoi. 37, 209-220. https://doi.org/10.1016/0008-8749(78)90188-0

Downloads

Published

2017-04-21

Issue

No. 2 (66) (2017)

Section

Veterinary medicine, quality and safety of livestock products

License

Relationship between right holders and users shall be governed by the terms of the license Creative Commons  Attribution – non-commercial – Distribution On Same Conditions 4.0 international (CC BY-NC-SA 4.0):https://creativecommons.org/licenses/by-nc-sa/4.0/deed.uk

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).