Study of microphloors of sleevicular tract for dysbiotic disorders in children of various age

Authors

  • T. V. Sklyar Oles Honchar Dnipro National University , Дніпровський національний університет імені Олеся Гончара
  • К. V. Lavrentieva Oles Honchar Dnipro National University , Дніпровський національний університет імені Олеся Гончара
  • M. V. Kolokolova Oles Honchar Dnipro National University , Дніпровський національний університет імені Олеся Гончара
  • V. Y. Chornobai Oles Honchar Dnipro National University , Дніпровський національний університет імені Олеся Гончара

DOI:

https://doi.org/10.31548/dopovidi2018.05.004

Abstract

In studying the quantitative and qualitative composition of the microflora of the gastrointestinal tract in children of all ages, dysbiotic disturbances were detected, and the most frequent was dysbiosis of the II degree - 48% of the number of persons with dysbiosis. Dysbiotic disorders were associated with the discovery of opportunistic strains of staphylococci and intestinal sticks. The studies on antibiotic resistance of staphylococci have shown a high level of resistance to ciprofloxacin - 60%, norfloxacin - 60%, and sensory strains were up to gentamicin and ampicillin - 80%. E. coli strains were resistant to norfloxacin - 90 and 92%, and ampicillin 60, 59%, and 59% and 59% for ceftriaxone and 58% and 59% for hematolytic and lactosonegative strains, respectively. In the study of phagosensitivity, integrated commercial drugs "Sektafag" and "Intesti-phage" were used, the effectiveness of which was 57 and 65% for staphylococci and 71, 58.1% for hemolytic and 81.2, 56.2% for lactosonegative strains of E. coli. .

Key words: staphylococcus, E. coli, antibiotic resistance, phagostimulation, dysbiosis, gastrointestinal tract

References

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Published

2018-11-06

Issue

No. 5(75) (2018)

Section

Biology, biotechnology, ecology

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