Динаміка показників антиоксидантного захисту в тканинах печінки молодняка перепелів за впливу аквахелатного розчину германію
Abstract
DYNAMICS OF INDICATORS OF ANTIOXIDANT PROTECTION IN LIVER TISSUE QUAIL UNDER THE INFLUENCE OF THE SOLUTION GERMANIUM
N. P. Nikchemenko, A. A. Emelyanenko, O. A Poroshinskaya,
L. S. Stovbeckaya, A. V. Emelyanenko, N. N. Samorai
Abstract. The article presents data on the effect the solution of Germanium aquahelates in various doses on the parameters of the antioxidant defense system, primary and secondary products of peroxidation, oxidative modification of proteins in the liver tissues of 1 and 5-day-old quails. According to the results of the study, it was established that of the solution of Germanium aquahelates affects the parameters of the antioxidant protection system in the liver's quails tissues and has a dose-dependent character. Thus, it was found that when using of the solution of Germanium aquahelates at a dose of 2.5 μg/kg in quails, the parameters studied were at the level of the control group, which indicates a weak dose effect. However, the applied water the solution of Germanium aquahelates at a dose of 5.0 μg / kg had a depressive effect on the formation of primary and secondary peroxidation products, significantly decreased the oxide protein modification (OPM) indices and positively influenced antioxidant defense enzymes during critical periods of quail development. At the same time, in the third test group, the at the solution of Germanium aquahelates a dose of 7.5 μg/kg had a retarding effect on the studied antioxidant protection indicators, which indicates a negative effect of this dose of the solution used during critical periods of quail development.
Keywords: the solution of Germanium aquahelates, young quails, superoxide dismutase, catalase, glutathione-peroxidase, middle mass molecules, oxide protein modification
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