Effectiveness of nano microelements preparation for correction of activity of antioxidant protection system in various types of high nervous activity

Authors

  • О.V. Danchuk National University of Life and Environmental Sciences of Ukraine image/svg+xml
  • V. І. Karpovsky National University of Life and Environmental Sciences of Ukraine image/svg+xml

Abstract

The article shows the effectiveness of nanoparticle treatment of trace elements Zn, Fe and Ge to correct the activity of the antioxidant system in pigs of different types of higher nervous activity. The work was carried out at the Department of Physiology, Pathophysiology and Immunology of the National University of Life and Environmental Sciences of Ukraine. The experiment was carried out in pigs of large white breed of different types of higher nervous activity.

The obtained results indicate that the release of nanoparticles of biogenic metals contributes to the increase of the activity of the enzymatic system of antioxidant protection in animals of different types of HNA. Under the influence of the technological stimulus, the activity of SOD and catalase in the red blood cells of the subactives is decreasing, depending on the type of HNA, respectively, on 15,7-21,8 % (p < 0,05 - 0,01). The injection of nanoparticles Zn, Fe and Ge substrates reduces the effect of the technological stress on the activity of enzymes of the antioxidant defense system, in particular, the activity of SOD in erythrocytes of blood subactives decreased during the day depending on the type of HNA 3.9-16.4 %.

Keywords: superoxide dismutase, catalase, higher nervous activity, pigs, stress

References

Saprin, A. N., Kalinina E. V., Saprin A. N. (1999). Okislitelnyiystressiegorolvmehanizmahapoptozairazvitiya patologicheskih protsessov [Oxidative stress - pathology or adaptation]. Usp. biol. Him.,39, 289–326.

Raha, S., Robinson, B. H. (2000). Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem. Sci, 25, 10, 502-508.

Danchuk, O.V. (2014). Indeks shyffoutvorennia u svynei riznykh typiv VND za dii tekhnolohichnykh stresiv [The index of шиффообразования in pigs of different types of GNI due to technological stresses]. Naukovyi visnyk LNUVM ta B im. Hzhytskoho. 16, 2 (59), 2, 89-93.

Danchuk, O. V. (2015). Aktyvnist katalazy ta superoksyddysmutazy u erytrotsytakh svynei riznykh typiv VND za tekhnolohichnoho stresu [Activity of catalase and superoxide dismutase in erythrocytes of different types of GNI pigs for technological stress]. Visnyk Sumskoho natsionalnoho ahrarnoho universytetu. Seriia «Veterynarna medytsyna», 7 (37), 33-36.

Sapryn, A. N., Kalynyna, E. V. (1999). Okyslytelnui stress y eho rol v mekhanyzmakh apoptoza y razvytyia patolohycheskykh protsessov [Oxidative stress and its role in mechanisms of apoptosis and development of pathological processes]. Usp. byol. khym., 39, 289-326.

Danchuk, O. V., Karpovskyi, V. I., Postoi, R. V., Trokoz, V. O. (2017). Vzaiemozviazky ta vplyv korkovykh protsesiv na aktyvnist superoksyddysmutazy v erytrotsytakh svynei za tekhnolohichnoho stresu [Interconnections and the effect of cortical processes on the activity of superoxide dismutase in pig red blood cells due to technological stress]. Naukovo – tekhnichnyi biuleten Derzhavnoho naukovo–doslidnoho kontrolnoho instytutu veterynarnykh preparativ ta kormovykh dobavok i Instytutu biolohii tvaryn, 18, 2. 13-17.

Trokoz, V. O., Karpovskyi, V. I., Trokoz, A. V., Puzyr, V. V., Vasyliv, A. P. (2012). Sposib vyznachennia typiv vyshchoi nervovoi diialnosti svynei [Method of determination of types of higher nervous activity of pigs]. Patent of Ukraine. A01K 67/00, A61D 99/00. №78853; – declared 04.11.2011, published 11.06.2012, №11.

Borysovych, V. B., Kaplunenko, V. H. (2009). Nanotekhnolohiia u veterynarnii medytsyni [Nanotechnology in veterinary medicine]. Kyiv. «Nanomaterialy i nanotekhnolohii», 232.

Kamyishnikov, V. S. (2002). Spravochnik po kliniko-biohimicheskoy laboratornoy diagnostike [Directory for clinical and biochemical laboratory diagnostics]. Minsk.:Belorus, 2, 463.

Published

2018-07-23

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