STRUCTURAL-FUNCTIONAL CHARACTERISTICS OF SPLEEN IN PIGLETS WITH SIGNS OF LATENT AND SUBCLINIC PCV2-INFECTION

Authors

  • V. Evert Dniprovsky State Agrarian and Economic University , Dniprovsky State Agrarian and Economic University

Abstract

The author, on the basis of pathohistological and
immunohistochemical studies, determined the structural and functional
characteristics of the spleen of piglets with signs of latent and subclinical
PCV2-infection. It has been established that in piglets with signs of subclinical
PCV2-infection, pathogistological changes of the spleen are specific for
different stages of the development of the infectious process and manifests
itself both at the tissue and cellular level of the organization, while in piglets
with signs of latent PCV2-infection, there are no significant differences in
comparison with clinically healthy, free of PCV-2.
Keywords: PCV2-infection, subclinical and latent forms, viral load,
spleen, immunohistochemistry

References

Gavrilina, O. G., Evert, V. V. (2016). Metodychni osoblyvosti zastosuvannia

imunohistokhimichnoi diahnostyky tsyrkovirusnoi infektsii svynei [Methodical features

of application of immunohistochemical diagnostics of circovirus infection of pigs].

Problems of animal science and veterinary medicine: Veterinary sciences. Collection

of scientific works of the Kharkov State Zooveterynary Academy, Kharkov, 32,

-301.

Goralsky, L. P., Khomich, V. T., Kononsky, O. I. (2011). Osnovy

histolohichnoi tekhniky i morfofunktsionalni metody doslidzhennia u normi ta pry

patolohii [Basis of histological technology and morphofunctional methods of dosage

in normology with pathology]. Zhitomir: Polissya, 288.

Alarcоn, P., Rushton, J., Wieland, B. (2013). Cost of post-weaning multi-

systemic wasting syndrome and porcine circovirus type-2 subclinical infection in

England - an economic disease model. Preventive Veterinary Medicine, 110, 88-102.

Doster, A., Subramaniam, S., Yhee, J., Kwon, B., Yu, C., Kwon, S.,

Osorio, F. (2010). Distribution and characterization of IL-10-secreting cells in

lymphoid tissues of PCV2-infected pigs. Journal of Veterinary Science, 11, 177-183.

Dvorak, C. M., Puvanendiran, S., Murtaugh, M.P. (2013). Cellular

pathogenesis of porcine circovirus type 2 infection. Virus Research, 174, 60-68.

Oliver-Ferrando, S., Segalеs, J., Lоpez-Soria, S. Callеn, A., Merdy, O.,

Joisel, F., Sibila, M. (2016). Evaluation of natural porcine circovirus type 2 (PCV2)

subclinical infection and seroconversion dynamics in piglets vaccinated at different

ages. Veterinary Research, 47, 121-140.

Chianini, F., Majо, N., Segales, J. Dominguez, J., Domingo, M. (2003).

Immunohistochemical characterisation of PCV2 associate lesions in lymphoid and

non-lymphoid tissues of pigs 185 with natural postweaning multisystemic wasting

syndrome (PMWS), Veterinary Immunology and Immunopathology, 94, 63-75.

Opriessnig, T., Meng, X. J., Halbur, P. G. (2007). Porcine circovirus type 2-

associted disease: Update on current terminology, clinical manifestations,

pathogenesis, diagnosis, and intervention strategies. Journal of Veterinary Diagnostic

Investigation, 19 (6), 591-615.

Published

2019-02-20

Issue

Section

Article