PATHOANATOMICAL CHANGES IN THE LAYING HENS ORGANISM AT MOSPILAN RP AND AKTARA 25 WG CHRONIC POISONING

Authors

  • G. Basaka National University of Bioresources and Nature Management Of Ukraine , National University of Bioresources and Nature Management Of Ukraine
  • B. Borysevich National University of Bioresources and Nature Management Of Ukraine , National University of Bioresources and Nature Management Of Ukraine
  • V. Dukhnitskiy National University of Bioresources and Nature Management Of Ukraine , National University of Bioresources and Nature Management Of Ukraine

Abstract

The article presents the results of pathoanatomical changes in
the laying hens organs at chronic experimental poisoning with neonicotinoids
Aktara 25 WG and Mospylan RP. It was found that when feeding laying hens
with feed containing Aktara 25 WG in different doses for 30 days caused
increase in the mass index of spleen, decrease of this index of heart and liver.
feeding laying hens with feed containing Mospylan RP in different doses for 30
days caused decrease of the mass indices of heart, liver, lung and glandular
and muscular parts of stomach.
Effect of Mospylan RP and Aktara 25 WG in doses of 65 mg/kg of body
weight and 360 mg/kg of body weight respectively caused microscopic
changes in hen’s kidneys such as serous glomerulonephritis, albuminous
degeneration and destruction of part of the tubules’ epitheliocytes; in liver –
edema, albuminous degeneration of hepatocytes; in the glandular part of the
stomach – significant damage of mucosa; and necrosis of the small intestine
mucosa. At preparations’ doses of 32.5 and 180 mg/kg of body weight
respectively, it was registered total necrosis of hepatocytes in most loci of the
liver. In those hens which were consumed feed contained Aktara 25 WG, it
was registered edema of gray and white substances of the brain, basophilia in
nerve cells and neuronophagy with the formation of glial nodules.
Keywords: neonicotinoids, Mospilan, Aktara, laying hens, chronic
toxicity, pathoanatomical changes

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Published

2019-03-05

Issue

No. 285 (2018)

Section

Article

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