CORRECTION OF ACTIVITY OF THE ANTIOXIDANT PROTECTION SYSTEM IN VARIOUS TYPES OF HIGH NERVOUS ACTIVITY BY THE TECHNOLOGICAL STRESS
Abstract
Nanoparticles of biogenic metals have a greater biological
activity than their molecular forms. The aim of the research was to determine
the effect of nanochelates Mg, Zn, Ge and Ce on the activity of the antioxidant
system in pigs of different types of higher nervous activity by the action of a
technological stimulus.
It was established that the activity of superoxide dismutase and catalase
in red blood cells of pigs of different types of higher nervous activity to the
effect of technological stimuli is not significantly different. After the action of a
technological stimulus, the activity of superoxide dismutase in red blood cells
of pigs is reduced by 15.7-21.8% (p <0.05-0.01), depending on the type of
higher nervous activity. As a result of the presentation of pigs to
nanoaquachelates, the effect of the technological stimulus to a lesser extent
influenced the activity of enzymes, thus, the activity of superoxide dismutase in
animals of a strong, well-balanced mobile, strong, balanced inert, severe
unbalanced and weak type of higher nervous activity decreases during the
day, respectively, by 3.9%, 10.8 %, 16.5% (p <0.05) and 16.4% (p <0.05).
Thus, the activity of superoxide dismutase in blood red blood cells of a strong,
well-balanced, mobile, strong, balanced, inert, strong, unbalanced and weak
type of higher nervous activity of the experimental group was higher (although
within the trend) by 14.0%, 9.4%, 5.2 % and 7.0% of the indexes of their
analogues from the control group.
Due to the release of biogenic metal nanochelates, the effect of the
technological stimulus contributed to the inadequate reduction of catalase
activity in red blood cells of pigs of different types of higher nervous activity (by
0.6-9.5%). The activity of catalase in erythrocytes of these animals was higher
in the range of 5.7-10.3% of the indexes of their analogues from the control
group.
Thus, the release of nanoparticles of metals significantly reduces the
effect of the technological stimulus on the activity of superoxide dismutase and
catalase in red blood cells of pigs.
Keywords: superoxide dismutase, catalase, nanoaquachelates,
higher nervous activity, pigs, stress
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