INFLUENCE OF WASHING-DISINFECTANT MEANS "ARGOMOL" ON THE ORGANISM OF LABORATORY ANIMALS (PRE-CLINICAL INVESTIGATION)

Authors

  • D. Zasiekin National University of Life and Environmental Sciences of Ukraine image/svg+xml
  • A. G. Pushkova National University of Life and Environmental Sciences of Ukraine image/svg+xml
  • R. O. Dymko National University of Life and Environmental Sciences of Ukraine image/svg+xml
  • V. L. Kovalenko State Scientific-Control Institute of Biotechnology and Strains microorganisms , State Scientific-Control Institute of Biotechnology and Strains microorganisms

Abstract

Milking equipment can be the main source of milk
contamination by microorganisms, since milk, which remains in the
unevenness of the milk line and separate parts of the apparatus, is a favorable
environment for the reproduction of microorganisms. Timely washing and
disinfection of milking equipment and dairy equipment is the key to obtaining
safe milk of high quality. We have developed a new washing-disinfectant
"Argomol" for the sanitation of milking equipment. When choosing a washer-
disinfectant for sanitation of dairy equipment, attention should be paid not only
to its effective bactericidal and other actions, but also to possible toxicity. This
article is devoted to the preclinical investigation of the washing-disinfectant
means "Argomol" for determining cumulative, irritating, sensitizing and skin-
resorptive actions of a remedy for the organism of laboratory animals. The
investigation were carried out according to the methodological
recommendations "Assessment of the suitability and effectiveness of
detergents, disinfectants and washing-disinfectants for the sanitary treatment
of milking equipment and dairy equipment". It is proved that the washing-
disinfectant means "Argomol" does not have a pronounced cumulative,
irritating, sensitizing and skin-resorptive effect. It is established that the
washing-disinfectant means "Argomol" according to the classification of
substances for toxicity (GOST 12.1.007-76) refers to the 4th toxicity class.
Keywords: washing-disinfectant, Argomol, toxicity, laboratory
animals

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Published

2019-03-05

Issue

No. 285 (2018)

Section

Article

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