MICROSCOPIC CHANGES IN LIVER AND PANCREAS OF DOGS AT THE INTESTINAL FORM OF PARVOVIRAL INFECTION

Authors

  • V. V. Lisova National University of Life and Environmental Sciences Of Ukraine , National University of Life and Environmental Sciences Of Ukraine
  • M. L. Radsikhovskiy Zhytomyr National Agroecological University , Zhytomyr National Agroecological University
  • A. O. Steblinova National University of Life and Environmental Sciences Of Ukraine , National University of Life and Environmental Sciences Of Ukraine

Abstract

Presented results of histological investigation of liver and
pancreas of 9 dogs died from the intestinal form of parvoviral infection. In the
liver slides, painted by hematoxylin and eosin, hepatocytes initially show
cellular swelling, which with the progressing of cellular damage turn into the
hydropic degeneration, which characterize by the lysis of cytoplasmic
structural components. After the lysis of lager part of cytoplasm cells
destroyed. Hydropic degeneration from the fatty change differentiated by the
painting by Sudan III. Degenerative changes of hepatocytes accompanied by
destroying of the trabecular structure of liver lobules and decreasing of the
lumen of sinusoid capillaries to the full obstruction of the part of such
capillaries. In the pancreas microscopic changes of exocrine part of organ was
irregular. The part of lobules has hypersecretion changes. In other lobules
acinar cells has things of cellular swelling. At the areas of swelling cells, there
was sites of its coagulative necrosis. In the pancreatic islands, there was the
swelling and coagulative necrotic changes of all types of insular cells. All this
microscopic changes permit to conclude, that the intestinal form of parvoviral
infection lead to the development of the hepatopancreatic syndrome.
Keywords: dogs, parvoviral infection, intestinal form, liver,
pancreas, microscopic changes, hepatopancreatic syndrome

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Published

2019-03-05

Issue

No. 285 (2018)

Section

Article

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