MORPHOLOGICAL CHANGES IN THE KIDNEYS OF PIGS WITH ACUTE COLIBACILLOSIS ON THE BACKGROUND OF EXCESS COPPER, IRON, COBALT
Abstract
Despite the introduction of new technologies of breeding and antimicrobial and specific means of combating with colibacillosis, this infection remains one of the most urgent problems of livestock. Circulating strains of E. coli have different antigenic structure and set of pathogenicity factors that determines the characteristics of their interaction with the host. In modern nomenclature, enterotoxins of esherihies divided into three main types: thermally labile, thermostable and shyha-like. The first two increases the permeability of cell membranes of intestinal epithelium, trigger diarrhea, the third inhibits protein synthesis by cells of the body with the formation of hemolytic uremic syndrome and hemorrhagic colitis.
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