Topography and morphology of the rabbit ileocecal patch.

Authors

  • O. Fedorenko National University of Life and Environmental Sciences of Ukraine image/svg+xml

DOI:

https://doi.org/10.31548/ujvs2019.02.052

Abstract

Rabbits have a very large cecum, that can hold up to 40 % of the intestinal contents,
which allows them to consume mainly high-fiber foods. One of the immune formations of this sec-
tion of large intestine is ileocecal plaque, which counteracts the antigenic influence of numerous
microorganisms. The samples were obtained from 12 clinically healthy males 4 months of age of
the white Panon breed. Material for histological examination was fixed in 6 % neutral buffered
formaline solution and embedded in paraffin. Sections (8–10 μm thick) were stained with hematox-
ylin and eosin, and according to Van Gieson. Microsoft Excel 2010 was used for statistical analysis.
The rabbit’s ileocecal plaque is located in the mucous membrane of the second haustra of cecum’s
base at its lesser curvature. One edge of this patch directly contacts with ileal papilla. It has an
oval shape and a length of 33.75±1.34 mm, and its largest width is 17.33±0.61 mm. The peyer's
patch has a yellowish color, clearly visible edges, and somewhat protrudes above the surface of the
intestinal mucosa. The largest area in the wall of the peyer's patches occupied the mucous mem-
brane (92.1±1.29 %). The muscular and serous membranes occupied a significantly smaller area –
5.34±0.69 % and 2.56±0.6 % respectively. Lymphoid tissue was represented by diffuse and nodular
forms. The nodular form occupied 70.27±5.44 % of its area. In the future it is planned to conduct a
study on lymphoid tissue cytological composition of the rabbit’s ileocecal plaque.
Keywords: rabbit, cecum, lymphoid tissue, lymph nodules, ileocecal plaque, Peyer's patch

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2019-05-30

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