Динаміка показників антиоксидантного захисту в тканинах печінки молодняка перепелів за впливу аквахелатного розчину германію



М. П. Ніщеменко, А. А. Ємельяненко, О. А. Порошинська, Л. С. Стовбецька, О. В. Ємельяненко, М. М. Саморай

Анотація


DYNAMICS OF INDICATORS OF ANTIOXIDANT PROTECTION IN LIVER TISSUE QUAIL UNDER THE INFLUENCE OF THE SOLUTION GERMANIUM

 

N. P. Nikchemenko, A. A. Emelyanenko, O. A Poroshinskaya,

L. S. Stovbeckaya, A. V. Emelyanenko, N. N. Samorai

 

Abstract. The article presents data on the effect  the solution of Germanium aquahelates in various doses on the parameters of the antioxidant defense system, primary and secondary products of peroxidation, oxidative modification of proteins in the liver tissues of 1 and 5-day-old quails. According to the results of the study, it was established that of the solution of Germanium aquahelates affects the parameters of the antioxidant protection system in the liver's quails tissues and has a dose-dependent character. Thus, it was found that when using of the solution of Germanium aquahelates at a dose of 2.5 μg/kg in quails, the parameters studied were at the level of the control group, which indicates a weak dose effect. However, the applied water the solution of Germanium aquahelates at a dose of 5.0 μg / kg had a depressive effect on the formation of primary and secondary peroxidation products, significantly decreased the oxide protein modification (OPM) indices and positively influenced antioxidant defense enzymes during critical periods of quail development. At the same time, in the third test group, the at the solution of Germanium aquahelates a dose of 7.5 μg/kg had a retarding effect on the studied antioxidant protection indicators, which indicates a negative effect of this dose of the solution used during critical periods of quail development.

Keywords: the solution of Germanium aquahelates, young quails, superoxide dismutase, catalase, glutathione-peroxidase, middle mass molecules, oxide protein modification


Повний текст:

PDF

Посилання


References

Volodkevych, S. V. (2013). Іnfluence of factors on productivity quail [Effect of equal factors on quail productivity] Modern poultry, 4,10-12.

Hlotov, I. (2013). "Karpatskyy quail" ... Figure quail, yes roads [Carpathian quail ]. Livestock Ukraine, 9, 6-9.

Kuznetsova, L. V., Babacan, V. D. Kharchenko, N. V. (2013). - Imunolohiia [Immunology: textbook ]. Ball: LLC "Mercury skirts".560.

Moskalenko, V. F., Jaworski, O. P., Tsekhmister Y.V. (2011). Pryrodni mekhanizmy dii nanomaterialiv: fizyko-khimichni, fiziolohichni, biokhimichni, farmakolohichni, toksykolohichni aspekty [Natural mechanisms of nanomaterials: physico-chemical, physiological, biochemical, pharmacological, toxicological aspects]Ukrainian Scientific Medical Youth Journal,4, 21-26.

Borisevich, B. B., Kaplunenko, V. G., Kosynov, N. V. [et al.] (2012). Nanomateryalы y nanotekhnolohyy v veterynarnoi praktyke [Nanomateryal and Nanotechnology in practice veterynarnoy] Kiev: WA "Avicenna",512.

Chen, D., T. Xi, Bai J.(2007). Biological effects induced by nanosilver particles: in vivo study [Biological effects induced by nanosilver particles: in vivo study]. Biomed. Mater, 3, 2. 126-128.

Chen, X. and Schluesener, H. J.(2008). Nanosilver: A nanoproduct in medical application. Toxicol Lett., Grodzik and Sawosza evaluated effect of silver 176: 1-12.


Метрики статей

Завантаження метрик ...

Metrics powered by PLOS ALM

Посилання

  • Поки немає зовнішніх посилань.