Environmental and comparison analysis of functional health of men of different age groups in radiation contaminated and conditionally pure regions

Abstract

The functional health of particular age groups, especially children, should be the main bio-indicator of the impact of integrated environmental pressure on the human body and regional socio-ecological status. Functional health levels are specific markers of the state of the organism adaptation to the changing conditions of the external and internal environment and, moreover, they reflect the general functional and vegetative homeostasis of the human body for the stability of which the autonomic nervous system is responsible for in the body. The purpose of the study was to investigate and compare functional health and autonomic balance in men of different age groups living in relatively clean and radiologically contaminated regions of Ukraine. The determination of vegetative status and orientation of vegetative activity in the body of men has been performed using functional vegetative diagnostics (FVD) according to the method of V. Makats. A total of 362 people of all ages were examined who underwent sanatorium and health improvement in the sanatoriums of Ukraine. The men were divided into 2 main observation groups. The first group resided in radiation-contaminated (RC) regions (Zhytomyr and Vinnytsia region), where they were classified according to the criteria of TRID-ELEUMH (thyroid irradiation dose exceeding the levels established by the Ministry of Health of Ukraine) and EEDHR (the effective equivalent dose of human radiation). The second group resided in relatively radiologically pure regions (Lviv region). In the method of functional-ecological examination (FEE) offered by us, the number of people (in %) in whom indicators of functional health are in states of functional depression (PA - parasympathetic activity advantage), vegetative equilibrium (VE) and number cases of the benefits of functional excitement (SA - the advantage of sympathetic activity) is the basis of systematic analysis. According to the criteria we have developed, human functional health is in the area of conditional norms, when 70% of people are in the zone of functional equilibrium (FE), and 15% are in the areas of parasympathetic and sympathetic activity. The analysis of the obtained data revealed that in the relatively pure regions of Ukraine only in the group of preschool men this figure is higher and reaches 75.6%, while in other groups it is significantly lower - in the group of young men of school age by 12.7% and mature age at 43.6%. The study of functional health in the functional equilibrium zone (FEZ) in radioactively contaminated regions of Ukraine revealed that in all observation groups the indicator is significantly below the developed norm: in the group of preschool men by 38.6%, adolescent school age by 46.4% and adulthood by 45.0%.

In the analysis of the data obtained during observation in male groups of different ages, it was found that in all groups the parasympathetic activity indicators significantly exceed the established norm of 15%, both in radio-contaminated and conditionally pure regions of Ukraine. But in the radio-contaminated regions of Ukraine, this indicator reaches a dangerous level and indicates a functional and ecological catastrophe. So in the group of preschool men it is higher 2.1 times, in the group of adolescent school age - 3.3 times and in the group of mature age - 4.1 times. It was also found that the mechanisms of functional and vegetative pathogenesis for all age groups of contaminated and conditionally clean regions are similar and have the same orientation and demonstrate the reliability of the proposed method.

 In the study of system-age dependence in male groups of preschool age 3-6 years, adolescent school age 12-15 years and mature age 21-50 years, living in relatively clean regions of Ukraine, it was found that the activity indicators of functional systems (FS) of the organism are almost coincided with similar indicators of age functional and vegetative norm. The result of the functional-ecological examination (FEE) of this group coincides with the criterion of radiation-free regions of Ukraine.

In the study of system-age dependence in the male group of preschool children 3-6 years old and mature age 21-50 years old living in radiation-contaminated regions the activity indicators of most functional systems (FS) of the organism has been found to be higher than the established age functional and vegetative forming disorders of the vegetative balance. In the study of system-age dependence in the male group of adolescent schoolchildren aged 12-15 years old living in radiation-contaminated regions, chaotic changes in FS activity were found, which are significantly higher or lower than the age functional and vegetative norm. This indicates a violation of the vegetative balance of the body and the processes of adaptation and accommodation.

   Age dispersion of vegetative levels of functional health of men of different age groups of radioactively contaminated and conditionally pure regions of Ukraine indicates a stable high level of its acceptable parasympathetic activity (PA) and unsatisfactory low level of functional equilibrium (FE). Their unsatisfactory levels, found in conditionally radiation-free regions of Ukraine, indicate an additional set of environmental pressures or the cumulative effect of its accumulation.