Safety analysis of drinking water on the test – organisms
DOI:
https://doi.org/10.31548/bio2019.03.004Keywords:
drinking water, biotesting, test organisms, cytotoxicity, white blood cell countAbstract
Providing the population with quality drinking water is an important task in maintaining human health. In world practice, when assessing water quality, in addition to chemical analysis, a total toxicological assessment of water is carried out, based on the use of various biotesting methods. Assessment of the quality of drinking water using bioassay methods in recent decades has gained particular relevance in connection with the rapid increase in the number of potentially dangerous chemical compounds that pollute natural sources of drinking water supply. The aim of the study was to assess the toxicity of drinking water from various sources of water supply (tap, artesian, packaged) using hematological parameters of test organisms: Danio rerio fish, Xenopus spur frogs and Wistar rats. It was revealed that the chemical composition of tap and bottled water did not meet the requirements of SanPiN 2.2.4-171-10 (State Sanitary and Hygienic Norm). Water from the water supply had an excess of Fe content (6.3 times), and bottled water. “Heavenly Krinitsa” exceeded Si and Mn (1.5 and 1.2 times, respectively). In the analysis of peripheral blood in experimental animals, these waters showed a cytotoxic effect – an increase in the number of monocytes, neutrophils and eosinophils and a decrease in lymphocytes. The detected changes in the cellular composition of the peripheral blood of experimental animals may indicate the activation of nonspecific natural resistance, the development of inflammatory and allergic reactions. Indicators of peripheral blood in test organisms that consumed water from the pump room were close to control.
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