Мікроскопічні зміни в печінці, нирках і підшлунковій залозі собак за експериментального ентерального саркоцистозу
Abstract
MICROSCOPIC CHANGES IN THE LIVER, KIDNEYS AND PANCREAS OF DOGS IN CASE OF EXPERIMENTAL ENTERAL SARCOCYSTOSIS
B. V. Borisevich, M. P. Prus, V. E. Zvorygina
Abstract.ResearchsonthedistributionofsarcocystosisamongdogsinUkrainehavenotbeencarriedout. Inanaccessibleworldliteraturepostmortemchangesincaseofsarcocystosisofdogsaredescribedinsufficiently. Theaimofourstudywastoexaminemicroscopicchangesintheliver, kidneysandpancreasofdogsincaseofexperimentalenteralsarcocystosis. Theliver, kidneyandpancreasofthreepups, experimentallyinfectedwithSarcocystis, wereusedinourinvestigation. Forhistologicalstudies, selectedpiecesofthoseorganswerefixedin 10% neutralaqueoussolutionofformalinand, afterdehydrationinethanolsofincreasingconcentrationsandchloroform, wereembeddedinparaffin. Sliceswiththicknessof 7 - 10 micronswereobtainedbyusingsledgemicrotome. Todetectmicroscopicstructureoforganssectionswerestainedwithhematoxylinandeosin.
Intheliverofdogs, incaseofexperimentalenteralsarcocystosis, granulardystrophyanddestructionofthehepatocytesandinterlobularproliferationoffibrousconnectivetissuewererecorded. Inkidneysextracapillaryserousglomerulonephritisandgranulardystrophyofepitheliumofconvolutedandstraighttubulesweredetected. Inthepancreasmicroscopicallytheswelling, disruptionanddestructionofindividualacinusoftheglandwerefoundout.
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