Дослідження вакцини інактивованої проти інфекційного ринотрахеїту великої рогатої худоби за показниками якості



М. М. Гулянич, В. В. Недосєков

Анотація


RESEARCH OF INACTIVATED VACCINE AGAINST INFECTIOUS BOVINE RHINOTRACHEITIS FOR QUALITY CRITERIA

M. M. Hulyanych, V. V. Nedosekov

Abstract. Infectious bovine rhinotracheitis is widespread throughout the world and causes significant losses in cattle industry. Vaccine is the main preventive measure in the fight against this disease in many countries. The article contains research results of quality criteria of vaccine against infectious bovine rhinotracheitis that we have developed from a selected in Ukraine strain "ВM". Laboratory methods established match of experimental batches of vaccine to local and international requirements for inactivated vaccines for animals. Presented results of the studies of chemical-physical and immunological parameters of quality of the developed vaccine. It has been established that vaccination of rabbits causes more than four-fold antibodies increase in serum of test animals, which is up to 21 days after vaccination averaged 8,06 log2.

Keywords: vaccine, vaccine prevention, infectious bovine rhinotracheitis, quality, laboratory studies

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References

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