Aссumulation specifics of enrofloxacin in organism of broiler chickens

Authors

  • N. V. Liniichuk Derzhavnyy Naukovo-Doslidnyy Instytut Z Laboratornoyi Diahnostyky Ta Veterynarno-Sanitarnoyi Ekspertyzy
  • O. M. Yakubchak National University of Life and Environmental Sciences of Ukraine
  • I. V. Galka Institute of Veterinary Medicine of the National Academy of Agrarian Sciences of Ukraine

Abstract

An experiment was conducted on broiler chickens, by oral administration of the veterinary drug "Baitril 10 %". The poultry of the control group was drunk by purified water, and the experimental group poultry - the preparation at the rate of 0.1 ml / kg of body weight for 5 days.

From the second day of the experiment, blood was sampled with further determination of the residual amount of enrofloxacin. On the third day of the experiment, the litter was collected and examined for antibiotic content. The poultry was slaughtered at 6, 12, 14 days after the last use of the drug.
Muscle tissue, skin and internal organs were selected and enrofloxacin was determined in them. A high performance liquid chromatography using a mass spectrometric detector (PX/MS/MS) was used for the study.

The analysis of the output of the active substance and the accumulation of it in the muscles and internal organs of the bird are carried out. In the blood, the amount of enrofloxacin exceeded 100 мg / kg for 15 days, in litter - 17 days. It has been established that the greatest amount of enrofloxacin is concentrated in the muscles of the wings, pectoral muscles, back muscles, thigh, shin, muscles of the back of the carcass and skin. Recomendations are given on the study of blood and litter before the slaughter of the bird.

Keywords: muscle tissue, internal organs, enrofloxacin, antibiotics, liquid chromatography using a mass spectrometric detector

References

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Published

2017-11-29

Issue

No. 273 (2017)

Section

Article

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