INFLUENCE OF VITAMIN AND AMINO ACID COMPLEX ON BIOCHEMICAL PARAMETERS OF PIGLETS IN EARLY POST-WEANING PERIOD

Authors

  • V. H. Yefimov Dniprovsky State Agrarian and Economic University
  • О. О. Lobochenko Dniprovsky State Agrarian and Economic University

Abstract

Changes in amino acid and vitamin metabolism in piglets in
the early post-weaning period require the search for effective means of
correction of metabolic processes. The purpose of the work was to study the
influence of the complex vitamin-amino acid preparation on the biochemical
parameters of piglets in the early post-weaning period.
It was formed according to the principle of similar groups, two groups of
piglets (240 animals in the experimental group and 133 in the control group). The
study was carried out on three-breeds hybrids (Large white × Landras × Duroc)
weaned on the 23rd day of life with a body weight of 6,2-7,4 kg. On the second day
after weaning the piglets of the experimental group put out a Vitamin-Amino Acid
Complex "Chicktonik" produced by Invesa (Spain) in the form of 0.5 % solution in a
dose of 3 ml per piglet for a day for 3 days by the Dosatron.
"Chicktonik" is a solution containing (per ml): vitamin A – 2500 IU,
vitamin D3 – 500 IU, α-tocopherol – 3.75 mg, vitamin B1 – 3.5 mg, vitamin B2
– 4 mg, vitamin B6 – 2 mg, vitamin B12 – 0,01 mg, sodium pantothenate – 15
mg; vitamin K3 – 0,250 mg, choline chloride – 0,4 mg, biotin – 0,002 mg,
inositol – 0,0025 mg, D,L-methionine – 5 mg, L-lysine – 2,5 mg, histidine – 0,9
mg , arginine – 0.49 mg, aspartic acid – 1.45 mg, threonine – 0.5 mg, serine –
0.68 mg, glutamic acid – 1.16 mg, prolin – 0.51 mg, glycine – 0.575 mg,
alanine – 0.975 mg, cystine – 0.15 mg, valine – 1.1 mg, leucine – 1.5 mg,
isoleucine – 0.125 mg, tyrosine – 0.34 mg, phenylalanine – 0.81 mg,
tryptophan – 0.075 mg.
Blood for biochemical studies was collected from the orbital sinus on 3
days after the end of the use of preparation. Biochemical blood parameters
were determined using the biochemical analyzer Miura (Italy) and the semi-
automatic biochemical analyzer Humalyzer 3000 (Germany) using the High
Technology (USA) reagent.
The level of total protein in the blood serum of animals was relatively low
and was within the range of 41-52 g/l. Analysis of the data shows that this is
due to the low content of globulin protein fractions. This is due, in our opinion,
to the destruction of colostral immunoglobulins. It was found that the
preparation led to a significant increase in albumin content in the serum of
piglets (by 9,8 % at P < 0,05). The lower level of creatinine (12.5 % at P <
0.05), established in the serum of piglets of the experimental group, is
probably related to a lower level of creatine degradation due to optimization of
bioenergetic processes in muscle tissue following the effect of preparation.
Lower creatinine content in serum may be associated with increased
anaerobic oxidation of glucose in the tissues of the body after use of
preparation. The level of glucose in experimental group piglets was higher by
19.9 % (P < 0.01) compared to control animals.
The content of total calcium in the blood serum of piglets receiving
"Chicktonik" was 6.4 % (P < 0.01). We found an increase in the activity of
alkaline phosphatase in the serum of piglets in the experimental group by 38.3
% (P < 0.05). These changes may be associated with an increase in metabolic
processes in the overall calcium fund against the background of higher rates of
bone growth, accompanied by high daily average weight gain.
It was found that the use of the complex vitamin-amino acid complex
"Chicktonik" for piglets in the early post-eating period leads to activation of the
protein synthesis in the liver and the increase of albumin content in serum, as
well as the increase of calcium-phosphorus metabolism, which is consistent
with the data on the increased requirement of vitamins and amino acids of
piglets after stress of weaning and requires further study of their metabolism in
the piglet organism due to the other effect of the additive.
Keywords: piglets, weaning, vitamins, amino acids, biochemical
parameters

References

Chumachenko, V. V. (2007). Biokhimichni ta imunolohichni osnovy systemy

profilaktyky stresu v svynei [Biochemical and immunological bases of stress prophylaxis

system in pigs]. National Agricultural University of Ukraine, Kyiv, 27.

Stoianovskyi, V. H., Matsiuk, O. I., Kolotnytskyi, V. A. (2017). Funktsionalna

adaptatsiia erytronu krovi porosiat za dii tekhnolohichnoho stresu [Functional adaptation of

piglets erythron after the effects of technological stress]. Abstracts book: XVI International

scientific and practical conference "Actual questions in veterinary medicine". Kyiv

(Ukraine), 86−87.

Danchuk, O. V., Karpovskyi, V. I., Danchuk, V. V. (2016). Indeksy intensyvnosti

peroksydnoho okysnennia lipidiv u svynei za dii stresovoho faktora [Indices of lipid

peroxidation intensity in pigs under the influence of stress factors]. Scientific Messenger of

Lviv National University of Veterinary Medicine and Biotechnology, 18 (1−2), 47−50.

Yefimov, V. H., Sofonova, D. M. (2014). Vikova dynamika kontsentratsii vitaminiv

A i E v syrovattsi krovi porosiat v period doroshchuvannia [Age dynamics of concentration

vitamins A and E in the serum of piglets during a rearing period]. Science and Technology

Bulletin of SRC for Biosafety and Environmental Control of AIC. 3 (4), 127−131, 46−50.

Pavlichenko, O. V., Chornyi, M. V. (2012). Vykorystannia adaptoheniv dlia

profilaktyky stresiv ta pidvyshchennia rezystentnosti tvaryn [Use of adaptogens to prevent

stress and increase animal resistance]. Problems of zooengineering and veterinary

medicine. 24 (1), 168−176.

Ohorodnyk, N. Z., Vishchur, O. I., Mizyk, V. P. (2015). Stan pryrodnykh

mekhanizmiv zakhystu u vidluchenykh porosiat za dii imunotropnoho preparatu [The state

of natural mechanisms of defence of weaning-piglets for actions of immunotropic

preparation]. Animal Biology. 17 (1), 78−84.

Tan, B., Li, X. G., Kong, X., Huang, R., Ruan, Z., Yao, K., Deng, Z., Xie, M.,

Shinzato, I., Yin, Y., Wu, G. (2009). Dietary L-arginine supplementation enhances the

immune status in early-weaned piglets. Amino Acids. 37 (2), 323−331.

Rezaei, R., Wang, W., Wu, Z., Dai, Z., Wang, J., Wu, G. (2013). Biochemical

and physiological bases for utilization of dietary amino acids by young pigs. Journal of

Animal Science and Biotechnology. 4 (7). doi : 10.1186/2049-1891-4-7.

Li, P., Yin, Y.-L., Li, D., Kim, S.W., Wu, G. (2007). Amino acids and immune

function. British Journal of Nutrition. 98, 237−252. doi : 10.1017/S000711450769936X.

Kolesneva, E. V., Bakakina, Yu. S., Sodel’, D. L., Zhornik, E. V., Baranova, L.

A., Dubovskaya, L. V., Volotovskiy, I. D. (2014). Geneticheskiy i proteomnyy analiz

khozyaystvenno poleznykh priznakov porod zhivotnykh [Genetic and proteomic analysis

for evaluation of economically useful traits among animal breeds]. Proceedings of the

National Academy of Sciences of Belarus. Biological series, 2, 89−97.

Published

2019-03-05

Issue

Section

Article