The effect of the preparations “Poledoxin” and “Tilmox 25%” on the biochemical blood parameters of broiler chickens

Authors

  • A.M. Tyshkivska National University of Life and Environmental Sciences of Ukraine image/svg+xml
  • V.B. Dukhnytskyi National University of Life and Environmental Sciences of Ukraine image/svg+xml
  • M.Y. Tyshkivsky Bila Tserkva National Agrarian University image/svg+xml
  • N.V. Tyshkivska Bila Tserkva National Agrarian University image/svg+xml

DOI:

https://doi.org/10.31548/poultry2020.07-08.007

Keywords:

"Poledoxin", "Tilmox 25%", broiler chickens, total protein, albumins, uric acid, creatinine, asparagine aminotransferase, alanine aminotransferase

Abstract

The results of studies of the effect of the drug "Poledoxin", belonging to the group of tetracycline and the drug "Tilmox 25%", belonging to the group of macrolides, on the biochemical parameters of the serum of broiler chickens cross "Cobb-500". It was found that the drugs "Poledoxin" and "Tilmox 25%", which were used in clinically healthy broiler chickens according to the scheme recommended for the treatment of birds with ornithobacteriosis and mixed infections, had a threshold effect on their body, without changes in clinical and behavioral status and reactions of birds. A study of the protein spectrum of poultry serum showed that under the influence of "Poledoxin" and "Tilmox 25%", develop hypoproteinemia due to a decrease in albumin levels by 10-53% (P≤0.05). In the serum of chickens of the first and second experimental groups, an increase in uric acid content by 11 and 8%, respectively (P≤0.05) was found 2 days after the use of antibiotics, and the maximum value exceeded the control by 21% (P≤0,05), is established in 3 days after the termination of their application. The content of creatinine in the serum of chickens fed antibiotic solutions increased, and after three days was higher than the birds of the control group by 6% (P≤ 0.05). 3 days after discontinuation of "Poledoxin", the content of creatinine in the serum of chickens of the first experimental group was higher than the control rate by 15%; and in second, which used "Tilmox 25%" – by 14% (P≤0.05). The study of mineral metabolism revealed a decrease in the content of inorganic phosphorus in the serum of poultry of the first experimental group by 10-19% (P≤0.05), the second – only a tendency to decrease.

Author Biography

  • A.M. Tyshkivska, National University of Life and Environmental Sciences of Ukraine
    post graduate student

References

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https://doi.org/10.3382/ps/pex036

Published

2021-01-18

Issue

Section

Veterinary Science