NONSPECIFIC FACTORS OF HUMORAL IMMUNITI IN ANIMALS FOR THE VACCINE «METAKOL»

Authors

  • T. B. Vasileva State Center for Innovative Biotechnology

DOI:

https://doi.org/10.31548/dopovidi2016.07.015

Keywords:

resistance, vaccination, immunoglobulins, microflora, antigens, antibodies, humoral immunity, serum, calves

Abstract

Colibacteriosis newborn calves is the most common disease that is registered in the last period significant number of farms in different regions of Ukraine. It should be noted that one of the main factors affecting the incidence calves colostrum is poor quality, due to the level of feeding calf cows and heifersQuestion colibacteriosis distribution becomes relevant.For the vaccination of animals is important immunobiological restructuring in animals, in particular, the state of nonspecific factors of protection. Vaccine is, to a certain extent, exogenous stress for animals, especially for young animals that can stimulate protective natural factors or suppressive effect on them. With this in mind, we conducted experimental studies on the effects of vaccine preparation for indicators of natural resistance of the organism in immunized animals.The proposed vaccine "Metakol" by immunization calf cows kolostral creates immunity in newborn calves.This paper presents the results of research impact vaccines' Metakol "on the body of cattle. The drug used for the prevention of colibacillosis in young cattle - heifers, newborns calves under thre3- days, 10-days and 24 days. The effect of the drug on colibacillosis prevention nonspecific factors of humoral immunity. After the vaccine pregnant heifers they increased level of natural protection as standard geteroagglyutinin level by 10.4% compared to unvaccinated cattle performance. Newborn calves and 3- 10 days old heifers vaccinated derived from normal antibodies titer levels increased by 50, 12.3 and 8.8% respectively. Vaccination of calves 10 days old vaccine "Metakol" has increased the geteroagglyutinin level 2.6 times compared to the figures of animals in the control group.It was established that the vaccine "Metakol" a positive effect nonspecific factors of humoral immunity in cattle of different age groups. The data demonstrate the effectiveness and feasibility of an experimental vaccine sample "Metakol" pregnant heifers and received from them offspring aged 10 days.

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Published

2016-12-28

Issue

No. 7 (64) (2016)

Section

Veterinary medicine, quality and safety of livestock products

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