RESULTS OF TREAMENT OF INFERTILE FEMALE DOGS

Abstract

The interest in the fertility of female dogs among veterinary specialists does not diminish. Scientists are continuously studying aspects of etiology, pathogenesis, clinical diagnosis and methods to overcome infertility in female dogs.

According to statistical data, the percentage of dogs with pathology of the reproductive system was 3.8-6% of the total pathology in the period 2008-2012 in Sumy.

Although many issues have been solved, the relevance of this problem, which is also of interest to owners of kennel dogs, is not reduced. Some patients fail to overcome infertility and identify causes.

The purpose of our study was to study the effectiveness of treatment of  infertility in  female dogs.

The investigated females were divided into several groups, depending on the type of pathology and method of treatment. Female pathology of the uterus was divided into two groups and treatment was carried out according to various schemes. The first group of unfertile females (n = 11) with uterine pathology was treated with injections of cephalosporins  into the internal lobe for 10 days and oxytocin at 0.5 U / kg subcutaneously for three days. Female dogs of the second group (n = 10) injected cephalosporins into the internal lobe for 10 days, aglepristone at a dose of 10 mg / kg subcutaneously on the 1st, 2nd, 8th day, cloprostenol 1 μg / kg 1 time per day, on the 3rd, 4th, 5th, 6th and 7th day of treatment. Females were given Karprofen subcutaneously at a dose of 3 mg / kg before inseminating a day.

The females with ovarian dysfunction were divided into four groups and treated with Ovarium Compositum, Tazalok, deslorelin, dydrogesterone.

In females with pathology of the ovaries of the first group (n = 4), we injected the drug "Ovaryum Compositum" subcutaneously in a dose of 1 ml a day from the beginning of the proestrus 5 times. Composition of the  medicine: Ovarium suis D8, Placenta suis D10, Uterus suis D10, Tummy gums, Hypophysis suis D13, Cypripedium calceolus var. pubescens, Lilium lancifolium D4, Pulsatilla pratensis D18, Aquilegia vulgaris D4, Sepia officinalis D10, Lachesis mutus D10, Apisinum D8, Creosotum D8, Calvatia gigantea D6, Cephalex ipecacuanha D6, Mercurius solubilis Hahnemann D10, Hydrastis canadensis D4, Acidum cis-aconiticum D10 , Magnesium phosphoricum D10.

In infertile females with ovarian pathology of the second group (n = 2), we used the implant "Suprellorin" subcutaneously for 6 months. The active substance of the drug is deslorelin acetat. Implant was surgically removed after 6 months.

In infertile females with ovarian pathology of  the third group (n = 6), we used the medicine "Tazalok" internally with 1 ml for 3 months. The medicine is a tincture of a mixture of medicinal plant material (1:10): the roots of the six-peal (Filipendula vulgaris Moench) - 0,28 g, the roots of parsley curly fresh (Petroselini radix) - 0,225 g, the roots of fresh celery (Apiumi radix) - 0, 17 g, the grass of the gentian (Galii herba) - 0.135 g, the grass of the flax of the usual (Linariae herba) - 0.11 g, Flowers Calendulae flowers - 0.08 g (extractant - ethanol 40%).

In infertile females with ovarian pathology of the fourth group (n = 4), we used the medicine "Dufaston" in 1 table. 1 days a day internally for three months. One tablet of the drug contains 10 mg of dydrogesterone (synthetic analogue of progesterone).

The control of the effectiveness of various methods of therapy was evaluated by us. We based on the results of the ultrasound study of the reproductive system and the breeding of infertile female dogs after our treatment.

We received offspring in 9.1% of the females of the first group,  after  our treatment of unfertile female dogs with pyometry or cystic hyperplasia of the uterus. The 27.3%  of the experimental female dogs had successful fertilization, but  9.1% of them had an early resorption of embryos and  9.1 % of them had dead puppies. In experimental female dogs of the second  group wich had uterine diseases, we had  litter from  one female after our treatment, accounting for 10% of the animals of the second group.  We observed cystic formations in the ovaries with ultrasound examination after treatment in 20% of experimental female dogs of the second group, the  40 % of them had cystic endometrial hyperplasia.

We see low rates of effectiveness the methods we used to overcome infertility of  female dogs of both groups.

We had litter from 75%  of female dogs  of the first group  with ovarian pathology.  The 25% females of this group were not fertilized, none with a controlled ultrasound had pathological changes in the ovaries or uterus. The female dogs of the second experimental group remained unfertile after our treatment. We did not receive litter from 100% experimental animals in the second group of females. We observed ovarian cysts and cystic hyperplasia of the uterus with ultrasonography in 50% of animals in this group. Assessing such results, it should be concluded that the effectiveness of the treatment of the second group was the lowest. Early embryo resorption and abortion were absent in any female dog.  We observed with control ultrasound cystic formations in the ovaries and cystic endometrial hyperplasia in 50% of experimental females of  the third group of female dogs after the treatment. After treatment, the 25 % of female dogs of the fourth group had litter. The 50% of female dogs of the fourth group  had cystic endometrial hyperplasia after treatment.

The most effective for overcoming the infertility of female dogs was the use of the drug "Ovarium Compositum" during proestrus. The inflammation in the uterus must be cured previously.